GPM™ Fermented Nutrients
Fermented, Functional, and Fully Absorbed.
Pharmachem’s GPM™ fermented nutrients represent the next generation of vitamins and minerals. Through a proprietary glycoprotein-matrix fermentation process, each nutrient is embedded in a whole-food matrix the body recognizes as food—absorbing and tolerating it more effectively than conventional USP or chelated forms.
Cutting-Edge Nutrient Innovation
This science-driven platform combines:
- Clinically studied bioavailability – human studies show markedly higher absorption versus USP salts and even many chelates.
- Gentle, food-like digestibility – naturally buffered for the stomach, ideal for sensitive populations.
- Clean-label appeal – Non-GMO, allergen-conscious, vegan/vegetarian, kosher and halal compliant, and “USDA Organic” or “Made with Organic” where applicable.
- Whole-food matrix with cofactors – peptides, enzymes, beta-glucans, and B-vitamins produced during fermentation for added immune and metabolic benefits.
- Formulation flexibility – stable in tablets, powders, gummies, beverages, and other formats.
Not just absorbed – Recognized.
Unlike isolated synthetics or engineered chelates, GPM™ nutrients mimic how vitamins and minerals occur in nature – boosting absorption, reducing GI discomfort, and elevating the consumer experience.
Flexible Formulations and Applications
GPM™ fermented nutrients are now available in a range of formulations to support nutritional needs. Applications span capsules and tablets to gummies, ready‑to‑mix powders, and stick packs.
GPM™ Core Fermented Nutrients
A cost-effective line of fermented nutrients which have been developed for over 2 decades. Clinical studies have shown their enhanced bioavailability and gentler digestion*.
GPM™ Organic Fermented Nutrients
Our portfolio of GPM™ Organic Fermented Nutrients includes a line of organic vitamins and minerals. These nutrients meet either USDA-certified organic standards or Made with Organic standards*. Instead of using synthetic ingredients, GPM™ Organic fermented nutrients are made as nature intended: bound with whole-foods and clean label, while free of the “Big 9” major food allergens.
GPM™ Biome Fermented Nutrients
The newest evolution of our platform adds the power of postbiotics to GPM™ nutrients for a dual-benefit solution—enhanced nutrient absorption and gut/immune support* in one clean-label ingredient. GPM™ Biome naturally generates beneficial postbiotics with clinically supported immune benefits*.
Introducing GPM™ Biome – Fermented Nutrients + Postbiotics
Fermentation helps your body recognize these nutrients as food, filling nutritional gaps more effectively while providing stable, postbiotic-driven immune support*.
- Gut microbiome support: Bioactive metabolites help balance gut flora and immune function.
- Clean-label & stable: Heat- and shelf-stable for all dosage forms.
- Science-forward differentiation: Clinical validation helps brands lead in microbiome innovation.
GPM Biome Fermented Nutrients are made using CSL Probiotics CRL1505 HI is a L. Rhamnosus strain, which has clinically tested results on improving immune system responses. During fermentation, yeast derived beta-glucans and postbiotics generated in this process aid gut health, tolerance, and immune support*. Based on clinical evidence, GPM™ Biome delivers the following health claims:
- Supports the immune system*
- Supports immune health*
- Supports immune function*
- Boost your immune system*
- Daily immune support* (if suggested use suggests daily intake)
Clinically Studied Results
In a double-blind, randomized trial published in Nutrients MDPI comparing GPM™ Fermented Zinc with standard zinc oxide, results showed that zinc bound to a glycoprotein matrix (GPM™) improved absorption while remaining gentle on the stomach:
- 40% greater absorption (iAUC) with GPM™ Fermented Zinc vs. zinc oxide
- Higher peak zinc levels (Cmax): 148 ± 21 mcg/dL vs. 135 ± 17.5 mcg/dL (p = 0.08)
- Sustained release: zinc levels remained significantly elevated at 120, 180, and 240 minutes with GPM™ fermented zinc
Findings from this study suggest that iron bound to a glycoprotein matrix (GPM™) can improve absorption kinetics without any associated side effects.
GPM™ Fermented Iron: ~27% greater absorption (AUC) vs chelates; Cmax +45% with ~15% faster Tmax.
GPM™ fermented vitamins, minerals, and pre-mixed blends currently available¹:
We provide a wide-range of fermented vitamins, minerals, and several premixed blends to help jump start your formulations:
- Beta Carotene
- Biotin
- Boron
- Calcium
- CoQ10
- Choline
- Chromium
- Copper
- Folic Acid
- Iodine
- Iron
- Lutein
- Magnesium
- Manganese
- Methyl Cobalamin
- Molybdenum
- Niacinamide
- Paba
- Pantothenic Acid
- Potassium
- Selenium
- Zinc
- Vitamin a
- Vitamin B1
- Vitamin B2
- Vitamin B6
- Vitamin C
- Vitamin D2
- Vitamin D3
- Vitamin E
- Vitamin K1
- Botanicals also available
Contact us to learn more about GPM™ fermented nutrients
Premixed Blends for Speed-to-Market
Beyond single fermented nutrients, Pharmachem offers ready-to-use GPM™ premixes to help brands launch faster:
- Women’s Multivitamin
- Men’s Multivitamin
- Prenatal vitamins (gentle on the stomach)
- Energizing vitamin blend
Our technical team can also create custom blends of any GPM™ fermented nutrients to meet brand-specific needs.
Partner with Pharmachem
At Pharmachem, we make ingredients work. From single ingredients to premixes and next-generation postbiotic platforms, our team is ready to bring your next innovation to life. Contact us to learn how GPM™ can elevate your formulations and your brand.
* US definition
¹ Benefits studies have not been done on all nutrients
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
