Prenulin™ Blend
Support healthy sugar metabolism with Prenulin™ blend. A combination of L-arabinose and Chromax® chromium picolinate, Prenulin™ blend supports healthy sugar management* in two ways.
Benefits
Prenulin™ Blend is unique because it works in two ways. Through the action of L-arabinose on the sucrase enzyme, it may reduce the breakdown of sucrose and with the inclusion of chromium, it may support control of insulin in healthy people.
L-arabinose is a monosaccharide found in non-starch carbohydrate component of plants like corn1,2. In vitro and animal studies have indicated that the compound may inhibit the enzyme sucrase that hydrolyses sugar and consequent digestion of sucrose3-6. A dose-response study1 showed a reduced serum glucose level and serum insulin response to sucrose consumption, indicating that the addition of L-arabinose helps to block the absorption of sugar.
Chromax® chromium picolinate may help to manage carbohydrate cravings. Pharmachem has incorporated Chromax® into our Prenulin™ Blend because of its superior bioavailability. In several clinical studies, Chromax® chromium picolinate has demonstrated that it is up to 15 times more bioavailable than other forms of chromium.
Advantages
- Can be formulated for oral consumption in tablets and capsules.*
- Use as part of a healthy diet to manage carbohydrate cravings and maintain a healthy weight.*
- One small study suggests that chromium picolinate may reduce the risk of insulin resistance.* And therefore possibly may reduce the risk of type 2 diabetes. FDA concludes, however, that the existence of such a relationship between chromium picolinate and either insulin resistance or type 2 diabetes is highly uncertain.
References
1 Krog-Mikkelsen, Hels, O, Inge, T, Holst, JJ, Andersen, JR, Bukhave, K. Am J Clin Nutr. 2011.
2 Budavani, S,(Ed.). (1989). The Merck Index: An Encyclopedia of Chemicals, Drugs, andnBiologicals (11th ed.). NJ: Merck.
3 Seri, K, Sanai, K, Matsuo, N, Kawakubo, K, Xue, C, Inoe, S. Metabolism. 1996.
4 Osaki, S, Kimura, T, Sugimoto, T, Hizukuri, S, Iritani, N. Nutrient Metabolism. 2000.
5 Preuss, HG, Echard, B, Bagchi, D, Stohs, S. Int J Med Sci. 2007.
6 Schutte, JB, de Jong, J, van Weerden, EJ, Tamminga, S. Br J Nutrition. 1992.
